Erectile dysfunction can be a common consequence of traumatic injuries, particularly pelvic, perineal or vertebral injuries. Generally the underling cause is damage to genital nerve function, and/or decreased penile bloodflow due to vascular injuries.

In some cases however trauma may not be due to injuries like falls or direct blow to the genital region. It can also be a consequence of treatment used to treat pelvic and perineal disorders, especially with surgeries for bladder, colorectal and prostate cancers, such as radical prostatectomy.